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Gustav Clark's avatar

I object. You're treading on my turf here. As a hard woking conservationist, botanist ecologist and coleopterist, I have never bought the anti-glyphosate message. The evidence against it is still so weak, and its opponentscs so obviously just pushing an anti-big-farming agenda. Deep down its just part of green romantic organic farming mythology that condems every increase in farm yields as unnatural.

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Rachel of Sunchoke Falls's avatar

I totally appreciate your willingness to chart your own course and do your own research. As an ecological landscaper, I myself am planning to get certified for herbicide application this winter - for targeted control of invasive species. (happy to discuss this angle with any haters out there). I think though that you may be glossing over some of the bigger picture concerns about glyphosate, at a global / biological systems level. I am not going to argue the toxicity claims - I trust your research. I've heard a number of different pieces / books about this. I can't remember where they all were so I had chatgpt just grab the key points covering the angles I do recall along with a relevant reference. Thanks.

1. Microbiome disruption (gut + system-wide effects)

Glyphosate can function as an antimicrobial and disrupt gut microbial balance in animal models, with implications for metabolic and immune health.

Source: Systematic review finds consistent evidence of microbiome alteration, dysbiosis, and intestinal effects.

📎 Food & Function Review, 2024

https://pubs.rsc.org/en/content/articlehtml/2024/fo/d4fo00660g

2. Soil microbial and fungal community shifts

Even low concentrations may alter soil microbial networks that regulate nutrient cycling, carbon sequestration and long-term soil fertility.

Source: Review identifies multiple pathways of microbial disruption and reduced biodiversity.

📎 CIRAD/INRAE biodiversity research summary, 2024

https://www.cirad.fr/en/cirad-news/news/2024/glyphosate-is-bad-for-biodiversity

3. Herbicide resistance and superweed evolution

Heavy reliance on glyphosate drives resistant weed species, locking agriculture into escalating chemical use.

Source: Agricultural and ecological review documents resistance feedback loops.

📎 PMC — Herbicide Resistance and Biodiversity

https://pmc.ncbi.nlm.nih.gov/articles/PMC5250645/

4. Narrowing of future agricultural options

A system built on low-cost herbicides may suppress development of alternatives like polycultures, crop rotations, and mechanical control.

Source: Modeling shows glyphosate-free systems involve tradeoffs but also ecological gains.

📎 Nature Scientific Reports, 2024

https://www.nature.com/articles/s41598-024-58183-8

5. Environmental persistence + aquatic ecosystem exposure

Runoff and soil binding may impact freshwater microbial webs, amphibians and invertebrates even where human toxicity is low.

Source: Broad review of glyphosate’s environmental pathways and trophic impacts.

📎 Frontiers in Microbiology, 2020

https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.556729/full

6. Gut–brain axis + neurological signaling

Early-stage rodent work suggests gut-mediated effects could influence neurotransmitters and behavior — not proven in humans, but worth tracking.

Source: Review highlights behavioral and neurochemical shifts linked to microbiome disruption.

📎 Frontiers in Toxicology, 2025

https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1704231/full

7. Metal chelation and nutrient availability

Glyphosate binds trace minerals — possible implications for plant micronutrient content and downstream nutrition. Evidence is mixed, but under-discussed.

Source: Overview of mechanisms including chelation and metabolic disruption.

📎 PMC — Glyphosate Review

https://pmc.ncbi.nlm.nih.gov/articles/PMC10561581/

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